Saint Francis High School is located on 43 acres just north of historic Alpharetta. The property is divided by Cooper Sandy Creek and contains several beautiful natural areas.

The Saint Francis High School campus includes a 42 classroom academic building, a separate lunchroom with a sandwich bar, a soup and salad bar, and daily hot meals, a gymnasium that seats 1,000 spectators and contains a full weight room and separate wrestling area, a baseball/softball field, soccer field, track, tennis courts and parking for over 350 cars. The campus also includes a library/media center, and an auditorium and performing arts center with instrumental music, choral music, and drama.